What is the success rate of statins?
Conclusions Patients who received statin treatment demonstrated a 20% to 30% reduction in death and major cardiovascular events compared with patients who received placebo. This advantage was generally present across study types and statin treatment types and for patients with less severe dyslipidemias.
How effective is statin treatment?
A review of scientific studies into the effectiveness of statins found around 1 in every 50 people who take the medicine for 5 years will avoid a serious event, such as a heart attack or stroke, as a result. Find out more about the side effects of statins.
Are statins effective at reducing cholesterol?
Statins are a type of medicine that are used to lower the cholesterol in your blood, helping to prevent heart disease and stroke. Statins often work very well. They can reduce your LDL cholesterol by around 30%, sometimes even 50% with high doses.
What is the evidence for statins?
Large-scale evidence from randomised trials shows that statin therapy reduces the risk of major vascular events (ie, coronary deaths or myocardial infarctions, strokes, and coronary revascularisation procedures) by about one-quarter for each mmol/L reduction in LDL cholesterol during each year (after the first) that it …
What are the disadvantages of taking statins?
What are statin side effects?
- Muscle pain and damage. One of the most common complaints of people taking statins is muscle pain.
- Liver damage. Occasionally, statin use could cause an increase in the level of enzymes that signal liver inflammation.
- Increased blood sugar or type 2 diabetes.
- Neurological side effects.
Are there any side effects to taking simvastatin?
It’s possible, although unlikely, that one particular statin may cause side effects for you while another statin won’t. It’s thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it’s taken at high doses.
Are there any active run in trials for simvastatin?
As a matter a fact, the SEARCH (Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine) trial, which included an active run-in, identified increased risk for myopathy with 80 mg of simvastatin daily. Moreover, most statin trials were designed with run-in phases involving the use of a placebo.
What do you need to know about statin side effects?
Statins block a substance your liver needs to make cholesterol. This causes your liver to remove cholesterol from your blood. If you think you’re experiencing side effects from statins, don’t just stop taking the pills. Talk to your doctor to see if a change of dosage or even a different type of medication might be helpful.
How many people take a statin a year?
Presuming that there hasn’t been a big drop off in use since 2005-2008 (the latest period for the government health survey upon which these statistics are based) almost 32 million Americans take a statin.