What is pachygyria syndrome?
Pachygyria is a developmental condition due to abnormal migration of nerve cells (neurons) in the developing brain and nervous system. With pachygyria, there are few gyri (the ridges between the wrinkles in the brain), and they are usually broad and flat.
Is pachygyria a progressive?
Pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures (PAMDDFS) is an autosomal recessive neurologic disorder characterized by progressive microcephaly associated with abnormal facial features, hypotonia, and variable global developmental delay with impaired intellectual …
What is Heterotopia in the brain?
Heterotopia means “out of place.” In normal brain development, neurons form in the periventricular region, located around fluid-filled cavities (ventricles) near the center of the brain. The neurons then migrate outward to form the exterior of the brain (cerebral cortex ) in six onion-like layers.
What causes Megalencephaly?
Megalencephaly occurs when your brain produces too many new brain cells or cells that are too large. It can also occur when metabolic byproducts and matter build up in your brain. Genetic factors and genetic disorders can cause megalencephaly.
What are the signs and symptoms of pachygyria?
  Pachygyria may occur alone (isolated) or as part of various underlying syndromes . Symptoms vary among affected people and may include moderate to severe developmental delay, seizures, poor muscle tone and control, feeding or swallowing difficulties, and small head size ( microcephaly ). 
What did syndrome say to mr.incredible?
” You, sir, truly are Mr. Incredible!” “All right, whom did you contact?” Syndrome mocking Mr. Incredible. Oh, this is just too good.” “He might make a good sidekick.” “This is not the end of it. I will get your son eventually. I will get your son!” Syndrome being sucked into the wind turbine of his aircraft. Full body of Syndrome.
Is there a connection between pseudobulbar palsy and pachygyria?
Pachygyria has also occurred in association with pseudobulbar palsy and intellectual disability in both children and adults.   The severity of symptoms associated with pachygyria varies depending on a variety of factors, including the location and size of the abnormality.
Can a person with pachygyria have epilepsy?
Pachygyria (macrogyria) has been diagnosed in adults with epilepsy.  Pachygyria has also occurred in association with pseudobulbar palsy and intellectual disability in both children and adults.