What is Microfollicular adenoma?
Follicular adenoma and follicular carcinoma of the thyroid gland are tumors of follicular cell differentiation that consist of a microfollicular architecture with follicles lined by cuboidal epithelial cells. A follicular adenoma is a benign encapsulated tumor of the thyroid gland.
Is follicular adenoma a cancer?
Follicular adenomas are a common benign neoplasm encountered in clinical practice. They usually present as a solitary thyroid nodule, but other presentations can occur in varied patients. It needs to be distinguished from follicular carcinoma, which is malignant and has a poor prognosis if undiagnosed.
What is a Microfollicular pattern?
The presence of predominant microfollicular pattern in smears could be seen in hyperplastic nodule, follicular neoplasm, FVPTC and thyroiditis. [6,7] These lesions are called as follicular lesions. In our study, microfollicular pattern was predominantly seen in follicular neoplasm.
What is heterogeneous lesion in thyroid?
Heterogeneous echogenicity of the thyroid gland has been associated with diffuse thyroid disease and benign and malignant nodules can coexist with diffuse thyroid disease. Underlying heterogeneous echogenicity might make it difficult to differentiate between benign and malignant nodules on US.
Do follicular adenomas grow?
The growth rates of follicular tumours on serial US were measured using at least 3 consecutive examinations during a median follow-up of 4.1 years (range, 0.7-13.3 years) by experienced radiologists.
Can thyroid adenomas become malignant?
New research published today in the Journal of the American Medical Association has concluded that even thyroid nodules that grow in size are unlikely to become cancerous.
What is benign follicular nodule?
Benign follicular nodule is a term pathologists use to describe a group of non-cancerous conditions in the thyroid gland. The conditions in this group include nodular thyroid hyperplasia, adenomatoid nodule, nodules in Graves’ disease, and follicular adenoma.
What causes a follicular adenoma in the thyroid?
Thyroid Follicular Cell Follicular Adenoma Hyperplasia Carcinoma Immunologic Basis of Follicular Nodules: TSH Receptor Antibodies • TSI stimulate hormone synthesis • TGI stimulate cell division Does TGI cause nodules in thyroiditis? Are they regenerative? Or are they neoplastic? Are they papillary ca? Definitions: Hyperplasia vs Neoplasia
What are the different types of thyroid follicular lesions?
Thyroid Follicular Cell Lesions: Hyperplasia vsNeoplasia • Nodular goiter • Hashimoto’s thyroiditis Which nodules are reactive/hyperplastic and which are neoplasms, benign or malignant? Classification: Follicular Adenomas •Simple • Microfollicular •Trabecular • Oxyphil • Atypical • Papillary • Signet ring cell *no prognostic significance
What is the microfollicular pattern of a thyroid nodule?
Benign thyroid nodules are characterized microscopically by a macrofollicular pattern which features large flat sheets of follicular cells with small dark round nuclei in a honeycomb arrangement, usually in a background of moderate to abundant colloid (Fig.
How many follicular cells are in a thyroid aspirate?
In contrast, thyroid aspirates composed of microfollicles (small follicular groups of 6–12 follicular cells in a ring with or without a small amount of central colloid), crowded trabeculae, or 3-D groups of overlapping follicular cells are a feature of follicular carcinomas as well as some adenomas (Fig. 2).