How is TB Medscape diagnosed?
Diagnosis. Screening methods for TB include the following: Mantoux tuberculin skin test with purified protein derivative (PPD) for active or latent infection (primary method) In vitro blood test based on interferon gamma release assay (IGRA) with antigens specific for Mycobacterium tuberculosis for latent infection.
What is tuberculosis Medscape?
Tuberculosis (TB) (see the image below), a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious disease–related mortality worldwide. Although TB rates are decreasing in the United States, the disease is becoming more common in many parts of the world.
What is the differential diagnosis of tuberculosis?
|Extra-Pulmonary Location||Differential Diagnosis|
|Tuberculous Arthrits||Bacterial septic arthritis, pseudogout|
|Central Nervous System Tuberculosis||Bacterial meningitis, viral meningitis, encephalitis|
|Tuberculosis Peritonitis||Bacterial peritonitis, chronic peritoneal dialysis|
Why is tuberculosis so difficult to treat explain?
Scientists have assumed that mycobacteria are so hard to kill because dormant cells exist even in patients with active disease and these cells are far less susceptible to antibiotics than metabolically active bacteria.
Is TB the same as pneumonia?
Pulmonary tuberculosis (PTB) is the most common, which can mainly cause lung injury and tubercles. PTB is a typical chronic consumptive disease, but it can present as an acute pneumonia. Acute tuberculous pneumonia (TP) is similar to typical bacterial pneumonia, and it is one of the causes of childhood illness .
What is the primary screening test for tuberculosis ( TB )?
The primary screening method for TB infection (active or latent) is the Mantoux tuberculin skin test with purified protein derivative (PPD). An in vitro blood test based on interferon-gamma release assay (IGRA) with antigens specific for M tuberculosis can also be used to screen for latent TB infection.
What are the symptoms of skeletal tuberculosis ( TB )?
Symptoms of skeletal TB may include the following: Back pain or stiffness Lower-extremity paralysis, in as many as half of patients with undiagnosed Pott disease Tuberculous arthritis, usually involving only 1 joint (most often the hip or knee, followed by the ankle, elbow, wrist, and shoulder)
Which is the best medicine for tuberculosis ( TB )?
1 A fluoroquinolone: levofloxacin or moxifloxacin preferred 2 Bedaquiline 3 Linezolid 4 Clofazimine (available only through Investigational New Drug application through FDA) 5 Cycloserine 6 An aminoglycoside: streptomycin or amikacin preferred 7 Ethambutol 8 Pyrazinamide 9 Delamanid 10 Ethionamide
What are the signs and symptoms of extrapulmonary tuberculosis?
Signs of extrapulmonary TB differ according to the tissues involved and may include the following: Confusion Coma Neurologic deficit Chorioretinitis Lymphadenopathy Cutaneous lesions